Oral vaccines:
The latest hot spot in the field of vaccine research is the development of vaccine which can be taken orally. Immunogenic protein of certain pathogens is found to be active when administered orally. The gene corresponding to such proteins is isolated and a gene construct is produced. This is introduced and expressed in a plant genome which results in production of such immunogenic proteins in the parts of the plant where it is expressed. These when fed into animals or mainly humans, the person becomes vaccinated against certain pathogen. Such vaccines are also known as edible vaccines. An exciting invention is production of ‘melt in the mouth’ vaccines that can be administered by placing them under your tongue which delivers it into the blood stream. The most important example is the production of flu vaccine by Bacillus which melts in the mouth. The tremendous benefit of such vaccines is the comfort of administration, low cost and ease of storage.
The latest hot spot in the field of vaccine research is the development of vaccine which can be taken orally. Immunogenic protein of certain pathogens is found to be active when administered orally. The gene corresponding to such proteins is isolated and a gene construct is produced. This is introduced and expressed in a plant genome which results in production of such immunogenic proteins in the parts of the plant where it is expressed. These when fed into animals or mainly humans, the person becomes vaccinated against certain pathogen. Such vaccines are also known as edible vaccines. An exciting invention is production of ‘melt in the mouth’ vaccines that can be administered by placing them under your tongue which delivers it into the blood stream. The most important example is the production of flu vaccine by Bacillus which melts in the mouth. The tremendous benefit of such vaccines is the comfort of administration, low cost and ease of storage.
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